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UCLA Eye Cancer Services

At UCLA, comprehensive clinical care for eye cancer is  provided primarily through the Ophthalmic Oncology Center, which is faciliated by the Jules Stein Eye Institute.

Consistently ranked as the best eye care center in the Western United States by U.S. News & World Report and Ophthalmology Times, the Jules Stein Eye Institute offers a full range of services for patients of all ages. Services are provided in private consultation with some of the most skilled and highly qualified eye and vision care specialists in the world.

The Ophthalmic Oncology Center

The Ophthalmic Oncology Center serves adults and children with tumors of the eye, eyelid and orbit. Patients with confirmed ocular melanoma are offered options for care that are often not available in the community. Options involve enucleation of the eye, radioactive plaque therapy, transpupillary thermotherapy (TTT) and laser surgery.

Treatment is closely coordinated with UCLA internists, oncologists and radiation oncologists. Patients with simulating diseases, such as common nevi, are closely followed by Center physicians. Full-time faculty members provide consultation and treatment, including surgical services. They have extensive, advanced training in ophthalmic subspecialties, which enables them to offer emerging therapies.

Collaborative Ocular Melanoma Study (COMS)

Melanoma of the eye and related or simulating diseases are the focus of a major research study in the Center, the Collaborative Ocular Melanoma Study (COMS), sponsored by the National Eye Institute. The COMS is a multicenter, randomized study to evaluate the effectiveness of standard treatment options, as well as treatment effects and quality of life. For medium-size choroidal melanoma, survival results of the clinical trial comparing enucleation with radioactive plaque therapy were published in 2001.

Clinical Trials

Clinical trials are carefully controlled research studies in which cancer patients help doctors and scientists find ways to improve health and cancer care, and to make sure the treatments are safe and effective. Each study is designed to address and answer specific scientific questions and to find better ways to prevent, diagnose or treat cancer. A clinical trial is one of the final stages resulting from the research conducted during intensive and lengthy laboratory studies.

Currently, over thirty separate studies at the Jules Stein Eye Institute are classified as patient-based or clinical research. These studies often represent the final stages of research prior to dissemination to the ophthalmology community for use with the general population. All studies have been reviewed and approved by the Federal Drug Administration and the UCLA Human Subject Protection Committee. Closely linked to the Institute's clinical and education programs, they offer patients an opportunity to participate in experimental treatment options and emerging therapies.

If you are interested in finding out more about these studies, visit our Clinical Trials Guide for general information and a listing of currently open clinical trials.

Additional Resources

Learn more about eye cancer services at UCLA by visiting the following related website:

Last updated: 5/19/2010 1:32:47 PM