The following new grants were awarded in March 2011:
Principal Investigator: Steve Bensinger
Sponsor Name: Margaret E. Early Medical Research Trust
Award Title: "Determining the Molecular Impact and Therapeutic Potential of the SREBP Pathway on Glioblastoma Multiforme"
Principal Investigator: Jonathan Braun
Sponsor Name: 2011-2012 California Health Interview Survey (CHIS)
Award Title: "Defining Functional Microbial Communities of the Human Mucosal-Luminal Interface and Their Role in Human Crohn's Disease"
Principal Investigator: E. R. Brown
Sponsor Name: Kaiser FDN Research Institute
Award Title: "2011-2012 California Health Interview Survey (CHIS)"
Principal Investigator: Bartosz Chmielowski
Sponsor Name: Ziopharm Oncology, Inc.
Award Title: "A Phase III Multicenter, International, Randomized, Double-Blind, Placebo-Controlled Study of Doxorubicin Plus Palifosfamide-Tris versus Doxorubicin Plus Placebo in Patients with Front-Line Metastatic Soft Tissue Sarcoma"
Principal Investigator: Timothy Cloughesy
Sponsor Name: Hoffman-La Roche Inc.
Award Title: "A Randomized, Double Blind, Placebo Controlled, Multicenter Phase Iii Trial of Bevacizumab, Temozolomide and Radiotherapy, Followed by Bevacizumab and Temozolomide versus Placebo, Temozolomide and Radiotherapy Followed by Placebo and Temozolomide in Patients with Newly Diagnosed Glioblastoma"
Principal Investigator: Oliver Dorigo
Sponsor Name: Morphotek, Inc. (Japan)
Award Title: "A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Assess the Efficacy and Safety of Weekly Morab-003 in Combination with Carboplatin and Taxane in Subjects with Platinum-Sensitive Ovarian Cancer in First Relapse"
Principal Investigator: Sarah Dry
Sponsor Name: College of American Pathologists Foundation
Award Title: "Research in Whole Slide Imaging"
Principal Investigator: Guoping Fan
Sponsor Name: NIH/National Institute of Neurological Disorders & Stroke
Award Title: "Mapping Dna Methylation in Hippocampal Neurons Through Bisulfite Sequencing"
Principal Investigator: Patricia Ganz
Sponsor Name: National Surgical Adjuvant Breast & Bowel Project Foundation
Award Title: "Examining Tumor Associated Macrophages in Breast Cancer Specimens"
Principal Investigator: J.R. Hecht
Sponsor Name: Keryx Biopharmaceuticals
Award Title: "A Phase Iii Randomized Double-Blind Study to Assess the Efficacy and Safety of Perifosine Plus Capecitabine versus Placebo Plus Capecitabine in Patient"
Principal Investigator: Jiaoti Huang
Sponsor Name: U.S. Army/Medical Research Acquisition Activity
Award Title: "The Function of Neuroendocrine Cells in Prostate Cancer"
Principal Investigator: Hanna Mikkola
Sponsor Name: Leukemia And Lymphoma Society (Leukemia Society Of America)
Award Title: "Mef2C in Hematopoietic Stem Cell Self-Renewal and Transformation"
Principal Investigator: Elizabeta Nemeth
Sponsor Name: NIH/National Heart, Lung and Blood Institute
Award Title: "The Role of Iron in Atherosclerosis: Application of New Iron Biology"
Principal Investigator: Ronald Paquette
Sponsor Name: Ariad Pharmaceuticals, Inc.
Award Title: "A Pivotal Phase 2 Trial of Ponatinib (Ap24534) in Patients with Refractory Chronic Myeloid Leukemia and Ph+ Acute Lymphoblastic Leukemia"
Principal Investigator: Antoni Ribas
Sponsor Name: Ariad Pharmaceuticals, Inc.
Award Title: "Bste-0709: Sample Collection of Whole Blood Plasma from Melanoma Cancer and Control Subjects"
Principal Investigator: Antoni Ribas
Sponsor Name: Alere Medical Incorporated
Award Title: "A Single-Arm, Open-Label, Expanded Access Study of Ro5185426 in Patients with Metastatic Melanoma"
Principal Investigator: Gary J. Schiller
Sponsor Name: Pharmamar Usa, Ltd.
Award Title: "Randomized, Multicenter, Open-Label, Phase Iii Study of Plitidepsin in Combination with Dexamethasone versus Dexamethasone Alone in Patients with Relapsed/Refractory Multiple Myeloma"
Principal Investigator: Gary J. Schiller
Sponsor Name: Chroma Therapeutics, Ltd. (Great Britain)
Award Title: "The Topaz Study: A Long Term Extension Study in Elderly Subjects with Relapsed/Refractory Acute Myeloid Leukemia to Allow Continued therapy with tosedostat"
Principal Investigator: Dennis Slamon
Sponsor Name: U.S. Army/Medical Research Acquisition Activity
Award Title: "An Integrated Program in Translational Research in Human Breast Cancer"