The following new grants were awarded to JCCC members in August 2011:
Principal Investigator: Utpal Banerjee
Sponsor Name: NIH/National Institute of Allergy and Infectious Diseases
Award Title: "A Drosophila Model for NFKB and Prostaglandin Dependent Inflammatory Response"
Principal Investigator: Kenneth Bradley
Sponsor Name: NIH/National Institute of General Medical Sciences
Award Title: "Cellular Intoxication Pathway of Cytolethal Distending Toxin"
Principal Investigator: Bartosz Chmielowski
Sponsor Name: Eisai America, Inc.
Award Title: "A Randomized, Open-label, Multicenter, Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Dacarbazine in Subjects With Soft Tissue Sarcoma"
Principal Investigator: Bartosz Chmielowski
Sponsor Name: Infinity Pharmaceuticals, Inc.
Award Title: "A Phase 2, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of IPI-926 in Patients With Metastatic or Locally Advanced (Unresectable) Chondrosarcoma"
Principal Investigator: Bartosz Chmielowski
Sponsor Name: Morphotek, Inc. (Japan)
Award Title: "A Study of the Efficacy and PK/PD Relationship of Monotherapy MORAb-004 in Subjects with Metastatic Melanoma"
Principal Investigator: Samson Chow
Sponsor Name: NIH/National Institute of General Medical Sciences
Award Title: "Role of HIV-1 In During Reverse Transcription and Uncoating"
Principal Investigator: Sven De Vos
Sponsor Name: Inc Research
Award Title: "A Phase 2 Study to Assess the Efficacy and Safety of CAL-101 in Patients with Indolent B-Cell Non-Hodgkin Lymphoma Refractory to Rituximab and Alkylating Agents"
Principal Investigator: Noah Federman
Sponsor Name: Pharmaceutical Research Associates, Inc.
Award Title: "An Open-Label, Multicenter Study of the Safety of Twice Daily Oxycodone Hydrochloride Controlled-Release Tables In Opioid Experienced Children from Ages 6 to 16 Years Old, Inclusive, with Moderate to Severe Malignant and/or Nonmalignant Pain Requiring Opioid Analgesic"
Principal Investigator: Richard Finn
Sponsor Name: Bayer/Columbia University
Award Title: "A Phase I Open-Label, Dose-Finding Study of BAY 43-9006 (Sofafenib) in High-Risk Hepatocellular Cancer Patients After Liver Transplantation"
Principal Investigator: Richard Finn
Sponsor Name: Meso Scale Discovery
Award Title: "Pharmacodynamic Assays for Cancer Therapeutics"
Principal Investigator: Richard Finn
Sponsor Name: Arqule Inc.
Award Title: "A Preclinical Research Program to Evaluate Predictors of Response for Arqule BRAF Inhibitor XXX"
Principal Investigator: John R. Froines
Sponsor Name: Clarence E. Heller Charitable Foundation
Award Title: "Risk and Decision: Evaluating Pesticide Approval in California"
Principal Investigator: Lillian Gelberg
Sponsor Name: Veterans Affairs (including VA Medical Centers)
Award Title: "The VA Assessment and Improvement Laboratory for Patient-Centered Care Project (Vail-PCC)"
Principal Investigator: David Heber
Sponsor Name: Hass Avocado Board
Award Title: "Hass Avocados Flesh Inhibition of Lipid Peroxidation Products When Added To A Ground Beef Patty Consumed By Health Volunteers"
Principal Investigator: Fairooz F. Kabbinavar
Sponsor Name: Bristol-Myers Squibb Company
Award Title: "A Randomized, Blinded, Phase 2 Dose-Ranging Study of BMS-936558 (MDX-1106) in Subjects with Progressive, Advanced/Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy"
Principal Investigator: Kasahara, Noriyuki
Sponsor Name: Cal Institute for Regenerative Medicine (CIRM)
Award Title: "Stem-Cell Based Carriers for RCR Vector Delivery to Glioblastoma"
Principal Investigator: Albert Lai
Sponsor Name: Millennium Pharmaceuticals, Inc.
Award Title: "Phase II Trial of Velcade (Bortezomib) in Combination With Temozolomide and Regional Radiation Therapy for Upfront Treatment of Patients with Newly-diagnosed Glioblastoma Multiforme"
Principal Investigator: Albert Lai
Sponsor Name: American Brain Tumor Association
Award Title: "Characterization of Mgmt Promoter Methylation Using an Episomal Cell Culture System (Fellow: Yiannis Philippou)"
Principal Investigator: Leonard S. Marks
Sponsor Name: NIH/National Cancer Institute
Award Title: "Biopsy Tracking and MRI Fusion to Enhance Imaging of Cancer Within the Prostate"
Principal Investigator: William H. McBride
Sponsor Name: U.S. Army/Medical Research Acquisition Activity
Award Title: "Radiation-Induced Vaccination to Breast Cancer"
Principal Investigator: Paul Mischel
Sponsor Name: Celgene Corporation
Award Title: "CC223 Research Plan for IHC Biomarker Studies"
Principal Investigator: Ronald T. Mitsuyasu
Sponsor Name: NIH/National Institute of Mental Health
Award Title: "South American Prevention of HIV Research Training Program (Saphir)"
Principal Investigator: Allan Pantuck
Sponsor Name: U.S. Army/Medical Research Acquisition Activity
Award Title: "Early Diagnosis of Clear Cell Kidney Cancer Via VHL/Hifpathway-Regulated Circulating Microrna"
Principal Investigator: Jeanette Papp
Sponsor Name: NIH/National Human Genome Research Institute
Award Title: "Middle School/Graduate School Joint Enrichment Partnership"
Principal Investigator: Kathrin Plath
Sponsor Name: NIH/National Institute of General Medical Sciences
Award Title: "Molecular and Architectural Mechanisms of Reprogramming to Pluripotency"
Principal Investigator: Caius G. Radu
Sponsor Name: NIH/National Cancer Institute
Award Title: "Novel Molecular Imaging Approaches to Monitor Gene and Cell-Based Therapies"
Principal Investigator: Yi Sun
Sponsor Name: Cal Institute for Regenerative Medicine (CIRM)
Award Title: "Studying Neurotransmission of Normal and Diseased Human ES Cell-Derived Neurons In Vivo"
Principal Investigator: Hsian-Rong Tseng
Sponsor Name: NIH/National Institute of General Medical Sciences
Award Title: "Generation of Hpscs Using Reprogramming Proteins-Encapsulated Nanoparticles"
Principal Investigator: Zev Wainberg
Sponsor Name: Amgen
Award Title: "A Phase 3, Multicenter, Randomized, Double-Blind, Placebo Controlled, Trial of AMG 479 or Placebo in Combination With Gemcitabine as First Line Therapy for Metastatic Adenocarcinoma of the Pancreas"
Principal Investigator: David Wong
Sponsor Name: UC Tobacco-Related Disease Research Program
Award Title: "Salivary Biomarkers Development for Detection of Lung Cancer"
Principal Investigator: Jerome A. Zack
Sponsor Name: NIH/National Institute of Allergy and Infectious Diseases/University of North Carolina
Award Title: "Eradication of HIV Reservoirs In Vivo"