The following new grants were awarded to JCCC members in November 2011:
Principal Investigator:
Belin, Thomas R
Sponsor Name: Eunice Kennedy Shriver National Institute of Child Health & Human Development/ University of California, Davis
Award Title: Bayesian Variable Selection in Generalized Linear Models with Missing Values
Principal Investigator: Bensinger, Steven
Sponsor Name: The Sontag Foundation
Award Title: Determining How Fat Fuels Growth in Glioma
Principal Investigator: Chmielowski, Bartosz
Sponsor Name: Icon Clinical Research Inc.
Award Title: A Phase 2 Study of a Human Anti-PDGFRA Monoclonal Antibody (Imc-3G3) in Previously Treated Patients with Unresectable and/or Metastatic Gastrointestinal Stromal Tumors (GIST)
Principal Investigator: Cloughesy, Timothy F
Sponsor Name: Celgene Corporation
Award Title: A Phase 1/2, Multi-Center, Open-Label, Dose Finding Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the mTOR Kinase Inhibitor CC-223 Administered Orally to Subjects With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma
Principal Investigator: Cloughesy, Timothy F
Sponsor Name: Novartis Pharmaceuticals/ Dana Farber Cancer Institute
Award Title: A Phase 2 Study of BKM120 for Subjects With Recurrent Glioblastoma and Activated PI3K Pathway at First Relapse
Principal Investigator: Cloughesy, Timothy F
Sponsor Name: Medimmune, Inc.
Award Title: A Phase 2 Study of Medi-575 in Adult Subjects with Recurrent Glioblastoma Multiforme
Principal Investigator: Dawson, David
Sponsor Name: American Cancer Society, Incorporated
Award Title: Regulation and Therapeutic Targeting Of WNT Signaling in Pancreatic Cancer
Principal Investigator: Mischel, Paul
Sponsor Name: Celgene Corporation
Award Title: Cc223 Pre-Clinical Study
Principal Investigator: Pantuck, Allan
Sponsor Name: Janssen Services, Llc.
Award Title: A Multicenter, Open-Label, Single-Arm, Phase 2 Study of Abiraterone Acetate Plus Prednisone in Subjects with Advanced Prostate Cancer Without Radiographic Evidence of Metastatic Disease
Principal Investigator: Plath, Kathrin
Sponsor Name: Cal Institute for Regenerative Medicine (CIRM)
Award Title: Discovery Of Mechanisms That Control Epigenetic States In Human Reprogramming and Pluripotent Cells
Principal Investigator: Plath, Kathrin
Sponsor Name: NIH/National Institute on Aging
Award Title: Aging and the Developmental Regulation of X Chromosome Inactivation
Principal Investigator: Schiller, Gary J
Sponsor Name: Cyclacel Pharmaceuticals, Inc (Incl Cyclacel Ltd)
Award Title: A Phase III Randomized Study of Oral Sapacitabine in Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia