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Funding Announcements: June 2012

The following new grants were awarded to JCCC members, announced in June 2012:

.Principal Investigator: Bower, Julienne

Sponsor Name: NIH/National Cancer Institute

Award Title: Biobehavioral Predictors of Fatigue in Newly-Diagnosed Breast Cancer Patients

Principal Investigator: Chmielowski, Bartosz

Sponsor Name: Incyte Genomics, Inc.

Award Title: Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumab in Combination With INCB024360 or Placebo in Subjects With Unresectable or Metastatic Melanoma

Principal Investigator: Cloughesy, Timothy

Sponsor Name: Pharmaceutical Product Development, Inc. (Ppd)

Award Title: Open-label, Phase I, Dose-escalation Study Evaluating the Safety and Tolerability of GDC-0084 Administered to Patients With Progressive or Recurrent High-grade Glioma

Principal Investigator: Cloughesy, Timothy

Sponsor Name: Tocagen, Inc.

Award Title: P1 Ascending Dose Trial of the Safety and Tolerability of Toca 511, a Retroviral Replicating Vector, Administered to Subjects at the Time of Resection for Recurrent High Grade Glioma and Followed by Treatment With Toca FC, Extended-Release 5-FC

Principal Investigator: Cloughesy, Timothy

Sponsor Name: Amgen

Award Title: Phase 1 First-in-Human Study Evaluating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 595 in Subjects With Recurrent Malignant Glioma Expressing Mutant Epidermal Growth Factor Receptor Variant III (EGFRVIII)

Principal Investigator: De Vos, Sven

Sponsor Name: Abbott Laboratories (Incl. Ross Laboratories)

Award Title: Phase 1b Study Evaluating the Safety and Pharmacokinetics of ABT-199 in Combination With Bendamustine/Rituximab (BR) in Subjects With Relapsed or Refractory Non-Hodgkin's Lymphoma

Principal Investigator: Dorigo, Oliver 

Sponsor Name: Charles R. Drew University of Medicine & Science

Award Title: Role of Macrophages in Ovarian Cancer 

Principal Investigator: Ellingson, Benjamin 

Sponsor Name: American College of Radiology 

Award Title: Independent Validation of Functional Diffusion Maps (FDMS) as a Biomarker for Glioblastoma Response to Therapy 

Principal Investigator: Ellingson, Benjamin

Sponsor Name: UC/Cancer Research Coordinating Committee (CRCC)

Award Title: Probabilistic Radiographic Atlas of Molecular and Interventional Phenotypes in Human Glioblastoma

Principal Investigator: Eradat, Herbert

Sponsor Name: Celgene Corporation

Award Title: Phase 3 Open-Label Randomized Study to Compare the Efficacy and Safety of Rituximab Plus Lenalidomide (CC-5013) Versus Rituximab Plus Chemotherapy Followed by Rituximab in Subjects With Previously Untreated Follicular Lymphoma. The "RELEVANCE" Trial (Rituximab Lenalidomide Versus Any Chemotherapy)

Principal Investigator: Eradat, Herbert

Sponsor Name: Abbott Laboratories (Incl. Ross Laboratories)

Award Title: Extension Study of Navitoclax (Abt-263) in Subjects with Chronic Lymphocytic Leukemia (CLL)

Principal Investigator: Garon, Edward 

Sponsor Name: Immunogen, Inc.

Award Title: Phase 1/2 Study to Assess the Safety and Efficacy of Lorvotuzumab Mertansine in Combination With Carboplatin/Etoposide in Patients With Advanced Solid Tumors Including Extensive Stage Small Cell Lung Cancer Official Title: A Phase 1/2 Study to Assess the Safety and Efficacy of Lorvotuzumab Mertansine (IMGN901) in Combination With Carboplatin/Etoposide in Patients With Advanced Solid Tumors Including Extensive Stage Small Cell Lung Cancer

Principal Investigator: Gasson, Judith

Sponsor Name: Jonsson Cancer Center Foundation

Award Title: AVON Cares for Life

Principal Investigator: Goldman, Jonathan

Sponsor Name: Synta Pharmaceuticals Corp.

Award Title: Phase 1 Study of The HSP90 Inhibitor, Ganetespib (Formerly STA-9090, Administered Twice-Weekly in Patients with Solid Tumors

Principal Investigator: Gomperts, Brigitte 

Sponsor Name: Children'S Hospital Corp. (The), Boston, Mass

Award Title: Genetic and Epigenetic Programming of Allergic Airway Inflammation

Principal Investigator: Graeber, Thomas

Sponsor Name: Melanoma Research Alliance

Award Title: Delineating BRAF Inhibitor Resistance Mechanisms Using Proteomic Profiling

Principal Investigator: Graeber, Thomas

Sponsor Name: UC/Cancer Research Coordinating Committee (CRCC)

Award Title: Co-Targeting Genomic Instability and Energy Metabolism in Breast Cancer

Principal Investigator: Heber, David

Sponsor Name: Icon Clinical Research Inc.

Award Title: Effect of Dulaglutide on Major Cardiovascular Events in Patients With Type 2 Diabetes: Researching Cardiovascular Events With a Weekly INcretin in Diabetes (REWIND)

Principal Investigator: Hurvitz, Sara

Sponsor Name: Optimer Pharmaceuticals, Inc.

Award Title: Double-Blind, Randomized Phase II Trial of Active Immunotherapy With Globo H-KLH (OPT-822) In Subjects With Metastatic Breast Cancer

Principal Investigator: Jacobsen, Steven

Sponsor Name: Jane Coffin Childs Memorial Fund

Award Title: Studies of 5.8S Ribosomal RNA Biogenesis and 5-Hydromethylcytosine Mapping

Principal Investigator: Kabbinavar, Fairooz

Sponsor Name: Eisai America, Inc.

Award Title: Open-Label, Multicenter, Phase 1b/2 Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior VEGF-Targeted Treatment

Principal Investigator: Kheifets, Leeka

Sponsor Name: Electric Power Research Institute (Epri)

Award Title: Asthma and EMF

Principal Investigator: Lai, Albert

Sponsor Name: American Brain Tumor Association

Award Title: Non-Invasive Circulation Free DNA Methylation-Based Biomarkers For Glioma Diagnosis and Surveillance

Principal Investigator: Lane, Timothy

Sponsor Name: UC/Cancer Research Coordinating Committee (CRCC)

Award Title: DCAF4 Is an Adaptor for CUL4:DDB1 Ubiguitin Ligase Activity in Cancer

Principal Investigator: Litwin, Mark

Sponsor Name: American Urological Association Foundation, Inc. 

Award Title: Chang, Lynne Ada: Impact of Hospital Transfer on Pediatric Testicular Torsion Outcomes

Principal Investigator: Lo, Roger

Sponsor Name: American Skin Association

Award Title: Rtk Coactivation In B-Raf Inhibitor Resistant Melanomas

Principal Investigator: Lo, Roger

Sponsor Name: The Melanoma Research Foundation

Award Title: Garg, Elisha: Rtk Coactivation in B-RAF Inhibitor Resistant Melanomas

Principal Investigator: Lo, Roger

Sponsor Name: Howard Hughes Medical Institute

Award Title: Garg, Elisha: Rtk Coactivation in B-RAF Inhibitor Resistant Melanomas

Principal Investigator: Memarzadeh, Sanaz

Sponsor Name: Sidney Kimmel Foundation for Cancer Research

Award Title: Kimmel Scholarship Award

Principal Investigator: Memarzadeh, Sanaz

Sponsor Name: Charles R. Drew University of Medicine & Science

Award Title: Preclinical Trial to Assess Effectiveness of PARP Inhibitors in Targeting Endometrial Cancer

Principal Investigator: Memarzadeh, Sanaz

Sponsor Name: Concern Foundation

Award Title: Potential Utility of a PARP Inhibitor in Targeting Endometrial Cancers

Principal Investigator: Memarzadeh, Sanaz

Sponsor Name: UC/Cancer Research Coordinating Committee (CRCC)

Award Title: Site Specific Role of Progesterone Anti-Tumor Actions in Endometrial Cancer

Principal Investigator: Mikkola, Hanna

Sponsor Name: Leukemia and Lymphoma Society (Leukemia Society of America)

Award Title: Transcriptional Mechanisms Establishing Hemogenic Endothelium

Principal Investigator: Nelson, Stanley

Sponsor Name: Guthy-Jackson Charitable Foundation

Award Title: Genome-Wide Association Study of Neuromyelitis Optica

Principal Investigator: Pantuck, Allan

Sponsor Name: Pom Wonderful LLC

Award Title: Novel Mitochondrially Encoded Peptides And Their Interaction with the Naturally Occuring Nutrients in Pomegranate

Principal Investigator: Pietras, Richard

Sponsor Name: UC/Cancer Research Coordinating Committee (CRCC)

Award Title: New Biologic Treatments for Human Pancreatic Cancer

Principal Investigator: Ponce, Ninez

Sponsor Name: Association of Asian Pacific Community Health Organizations

Award Title: Patient-Centered Outcomes Research in Community Health Centers

Principal Investigator: Reiter, Robert

Sponsor Name: Takeda Pharmaceutical Company, Limited

Award Title: Evaluation of Candidate EMTGenes

Principal Investigator: Rettig, Matthew

Sponsor Name: Exelixis, Inc.

Award Title: Phase 3, Randomized, Double-blind, Controlled Trial of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously Treated Symptomatic Castration-resistant Prostate Cancer

Principal Investigator: Ribas, Antoni 

Sponsor Name: Phase One Foundation

Award Title: Phase 1 Study of Gene Modified Immune Cells and A Ctla4 Antibody in Patients With Advanced Melanoma

Principal Investigator: Rosen, Lee

Sponsor Name: Vegenics Limited (Australia)

Award Title: Phase I, Open Label, Dose Escalation Study of the VEGF-C Human Monoclonal Antibody VGX-100 Administered by Intravenous Infusion Alone and Co-administered With Bevacizumab in Adult Subjects With Advanced or Metastatic Solid Tumors

Principal Investigator: Rosen, Lee

Sponsor Name: Millennium Pharmaceuticals, Inc.

Award Title: Phase 1 Study of Oral MLN9708 to Assess Drug-Drug Interaction With Ketoconazole, Relative Bioavailability, Food Effect, and Safety and Tolerability in Patients With Advanced Nonhematologic Malignancies, Lymphoma, or Waldenstrom's Macroglobulinemia

Principal Investigator: Rosen, Lee

Sponsor Name: Oncomed Pharmaceuticals, Inc

Award Title: Phase 1 Dose Escalation Study of Omp-18R5 in Subjects with Solid Tumors

Principal Investigator: Schiller, Gary

Sponsor Name: Sanofi-Aventis Group (Incl Sanofi Synthelabo, Aventis Pasteu

Award Title: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, 3-Arm Study of SAR302503 in Patients With Intermediate-2 or High-Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis With Splenomegaly

Principal Investigator: Schiller, Gary

Sponsor Name: Astellas Pharma US LLC (Inc. Astellas Pharma, Inc.)

Award Title: Phase 2, Randomized, Open-Label Study of the Safety and Efficacy of Two Doses of Quizartinib (AC220; ASP2689) in Subjects With FLT3-ITD Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Principal Investigator: Sloan, Erica

Sponsor Name: NIH/National Cancer Institute

Award Title: Adrenergic Regulation of Tumor Inflammation and Metastatic Dissemination

Principal Investigator: Van Dam, Robert

Sponsor Name: Sofie Biosciences, Inc.

Award Title: Commercialization of a Benchtop Radiosynthesizer for the Production of PET Probes for Imaging of Brain Disorders

Principal Investigator: Wu, Lily

Sponsor Name: U.S. Army/Medical Research Acquisition Activity

Award Title: Disrupting The Pro-Tumorigenic Influences of Tumor-Infiltrating Myeloid Cells by CSF1R Blockade to Augment Androgen Deprivation Therapy in Prostate Cancer

Principal Investigator: Zeng, Gang

Sponsor Name: NIH/National Cancer Institute

Award Title: A+PSA Assay for Improved Prostate Cancer Diagnosis and Risk Assessment

 

Last updated: 12/17/2014 5:29:02 PM