Director: Gang Li, Ph.D.
Co-Director: Robert Elashoff, Ph.D.
AV-357 Center for Health Sciences
University of California, Los Angeles
Los Angeles, CA 90095-1766
Telephone: (310) 794-5861
Fax: (310) 267-2611
The mission of BASE is to provide statistical analysis and study design services to the UCLA Cancer Center community.
Biostatistical Study Support
BASE serves as the biostatistical and biomathematical resource for UCLA's Jonsson Comprehensive Cancer Center (JCCC) investigators in the areas of basic science, translational and clinical research design, data analysis and modeling, computing, and data management. In addition to standard statistical expertise, BASE can provide expert statistical collaboration on topics including pharmacokinetics, tissue array, clinical trials, microarray analysis, imaging analysis and proteomic analysis.
Guidance in Grant Preparation
BASE faculty can assist individual Cancer Center investigators in grant preparation. We can provide general guidance in terms of study design (experimental design, measurement, etc), sample size calculations and development of statistical analysis sections. In addition to assistance with grant preparation, BASE faculty are generally available to serve as co-investigators on grant applications and can provide long term collaboration for funded projects.
Details of BASE Unit Services
Long-Term Study Collaboration
Collaboration on projects from inception (typically at the grant preparation stage) through final manuscript submissions. For this we can provide assistance with the grant preparation, study planning, data management oversight data analytic support and collaboration on manuscript preparation. Typically for long-term collaborations BASE faculty and staff will be involved on the grant application (or can be added to funded projects) with percent effort funding appropriate to their project responsibilities.
Provides a stable resource of productive biostatistical and biomathematical faculty and staff capable of short-term consulting with JCCC members in specific program areas. Short-term consulting typically consists of at most five hours of consultation with data analysis and manuscript preparation. Large analytic projects will typically require funding support for the BASE member(s) providing assistance.
Other BASE Unit Functions
- BASE members provide critical expertise to protocol review and approval functions of the Internal Scientific Peer Review Committee (ISPRC), Data Safety and Monitoring Board (DSMB), the Internal Quality Assurance Committee and the Seed Grant Review Committee.
- BASE faculty are available for assistance with TRIO-US trials
- Develops graduate student participation in cancer-related studies supervised by BASE and provide training to fellows and faculty in the design and conduct of research.
- Assists JCCC and other specialized centers in their research and reporting functions.
- Providing statistics short courses and seminars to interested groups within the JCCC
Joint Partnership with JCCC Shared Resources
The JCCC Genomics/UCLA Clinical Microarray Core (CMC) and BASE are pleased to announce a formal strategic partnership. This partnership will significantly strengthen JCCC's next generation sequencing/Microarray capability. Under this agreement, CMC will perform the wet-lab sequencing/microarray and initial/standardized data analysis whereas BASE will perform the advanced/customized data analysis. Please visit the JCCC Genomics shared resource.
Service Request Protocol
Requests to BASE for consulting services to Cancer Center investigators are initiated by telephone or email, either to the Director or to one of the BASE faculty. If the request is short-term (simple data analysis, simple design problem, isolated manuscript review, etc.) and not part of pre-existing collaborative work with a BASE member, the inquiry is referred to the BASE member covering that program area or a related area.
- Initial Contact: Email the Director (email@example.com) or the primary BASE faculty contact covering that program area to set up a meeting.
- After it is determined that our services are required, BASE will contact you within one week on how to proceed about your project.
- An expert in the field will be assigned to the project depending on the field.
Biostatistical support is available to all Cancer Center Members and their laboratories. Peer-reviewed, funded research projects of JCCC investigators represent the highest priority. Short-term tasks of interest to individual investigators that do not have available funding for statistical co-investigators are given some support on a first-come, first-served basis.
| JCCC Rate (hourly)|
|Consultation with BASE SR member listed a co-PI on a grant
|Consultation (first five hours)
|Consultation (beyond five hours)
BASE consists of seven faculty members and twelve staff members.
Primary Faculty Contact by Program Areas*
|JCCC PROGRAM AREAS
|| Primary base unit faculty contact info|
|Cancer and Stem Cell Biology
Cancer Molecular Imaging
Signal Transduction and Therapeutics
|Dr. David Elashoff|
(Tel: 47595; Email: firstname.lastname@example.org)
Dr. Steve Horvath
(Tel: 49299; Email: email@example.com)
Dr. Robert Elashoff
(Tel: 59421; Email: firstname.lastname@example.org)
Dr. Gang Li
(Tel: 65865; Email: email@example.com)
|Healthy and At-Risk Populations
Patients and Survivors
Dr. Catherine Crespi
(Tel: 69364; Email: firstname.lastname@example.org)
Note: *If you have an established collaboration with BASE faculty, you may continue your collaboration with the faculty even if he/she is not listed as the primary faculty contact for your program area.