Scientific Interest(s):
Dr. David Heber's research is focused on the role of nutrition, botanical dietary supplements and the prevention and treatment of obesity in common forms of cancer, including breast and prostate cancer.
Heber and his colleagues are currently studying a botanical dietary supplement for its application to prostate cancer prevention, green tea supplementation and the treatment of obesity to prevent recurrence of breast cancer and the impact of phytochemicals from fruits, vegetables, and green tea on the multistep process of carcinogenesis in models relevant to common forms of cancer.
Selected Cancer-Related Publications:
Early JL, Apovian CM, Aronne LJ, Fernstrom MH, Frank A, Greenway FL, Heber D, Kushner RF, Cwik KM, Walch JK, Hewkin AC, Blakesley V. Sibutramine plus meal replacement therapy for body weight loss and maintenance in obese patients. Obesity (Silver Spring). 2007; 15(6): 1464-72.
Kumagai T, Muller CI, Desmond JC, Imai Y, Heber D, Koeffler HP. Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. Leuk Res. 2007; 31(4): 523-30.
Li Z, Hong K, Wong E, Maxwell M, Heber D. Weight cycling in a very low-calorie diet programme has no effect on weight loss velocity, blood pressure and serum lipid profile. Diabetes Obes Metab. 2007; 9(3): 379-85.
Li Z, Aronson WJ, Arteaga JR, Hong K, Thames G, Henning SM, Liu W, Elashoff R, Ashley JM, Heber D. Feasibility of a low-fat/high-fiber diet intervention with soy supplementation in prostate cancer patients after prostatectomy. Eur J Clin Nutr. 2007.
Lu QY, Jin YS, Zhang ZF, Le AD, Heber D, Li FP, Dubinett SM, Rao JY. Green tea induces annexin-I expression in human lung adenocarcinoma A549 cells: involvement of annexin-I in actin remodeling. Lab Invest. 2007; 87(5): 456-65.