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JCCC Member Directory

Linda Liau, M.D., Ph.D.
Linda Liau, M.D., Ph.D.

Specialty:

Neurological Surgery

General Information:

Gender:
Female
Language(s):
English

Affiliation(s):

Professor, Department of Surgery, Neurosurgery
Physician, Department of Surgery, Neurosurgery
Member, JCCC Tumor Immunology Program Area

Hospital Affiliation(s):

Ronald Reagan UCLA Medical Center

Education:

Fellowship:
Neuro-Oncology, UCLA School of Medicine, 1998 - 1998
Residency:
Surgery/Neurosurgery, UCLA School of Medicine, 1992 - 1997
Internship:
Surgery, UCLA School of Medicine, 1991 - 1992
Medical Degree:
M.D., Stanford University School of Medicine, 1991
Degree:
Ph.D., UCLA, 1999

Certification(s):

Medical Board Certification(s):
Neurological Surgery, American Board of Neurological Surgery, 2002

Contact Information:

Surgery:
(310) 794-7788 Patient appointments
Neurosurgery:
(310) 825-5111 General information and referral
Comprehensive Brain Tumor Program:
(310) 825-5111 General information and referral
Phone:
(310) 267-2621
Email:
Website:

Practice Information:

Clinical Interest(s):
Brain Tumor

Scientific Interest(s):

Dr. Linda Liau's research efforts are focused on gene therapy and immunotherapy approaches in treating patients with malignant brain tumors.

Selected Cancer-Related Publications:

Prins RM, Cloughesy TF, Liau LM. Cytomegalovirus immunity after vaccination with autologous glioblastoma lysate. N Engl J Med. 2008 Jul 31;359(5):539-41.

Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, Du J, Kau T, Thomas RK, Shah K, Soto H, Perner S, Prensner J, Debiasi RM, Demichelis F, Hatton C, Rubin MA, Garraway LA, Nelson SF, Liau L, Mischel PS, Cloughesy TF, Meyerson M, Golub TA, Lander ES, Mellinghoff IK, Sellers WR. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20007-12. Epub 2007 Dec 6.

Thomas RK, Baker AC, Debiasi RM, Winckler W, Laframboise T, Lin WM, Wang M, Feng W, Zander T, Macconnaill LE, Lee JC, Nicoletti R, Hatton C, Goyette M, Girard L, Majmudar K, Ziaugra L, Wong KK, Gabriel S, Beroukhim R, Peyton M, Barretina J, Dutt A, Emery C, Greulich H, Shah K, Sasaki H, Gazdar A, Minna J, Armstrong SA, Mellinghoff IK, Hodi FS, Dranoff G, Mischel PS, Cloughesy TF, Nelson SF, Liau LM, Mertz K, Rubin MA, Moch H, Loda M, Catalona W, Fletcher J, Signoretti S, Kaye F, Anderson KC, Demetri GD, Dummer R, Wagner S, Herlyn M, Sellers WR, Meyerson M, Garraway LA, MacConaill L. High-throughput oncogene mutation profiling in human cancer. Nat Genet. 2007.

Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF, Sawyers CL, Mischel PS. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med. 2005; 353(19): 2012-24.

Liau LM, Prins RM, Kiertscher SM, Odesa SK, Kremen TJ, Giovannone AJ, Lin JW, Chute DJ, Mischel PS, Cloughesy TF, Roth MD. Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment. Clin Cancer Res. 2005; 11(15): 5515-25.