UCLA's Jonsson Comprehensive Cancer Center : JCCC Member Directory

Noah Craft, M.D., Ph.D.

General Information:

Gender:	Male
Language(s):	English

Affiliation(s):

Assistant Professor, Harbor-UCLA Department of Medicine, Division of Dermatology

Associate Program Director, Dermatology

Director, Guenther Center for Immunotherapeutics Research

Member, Los Angeles Biomedical Research Institute

Member, JCCC Tumor Immunology Program Area

Education:

Fellowship:	Dermatology and Microbiology, Immunology, and Molecular Genetics, UCLA, 2001 - 2005
Residency:	Dermatology, UCLA/West Los Angeles Veterans Affairs Medical Center, 2001 - 2005
Internship:	Internal Medicine, UCLA/Olive View County Hospital, 2000 - 2001
Medical Degree:	M.D., UCLA School of Medicine, 2000
Degree:	Ph.D., UCLA Molecular Biology Institute, 2000

Contact Information:

Phone:	(310) 781-1447
Email:	ncraft@ucla.edu
Website:	http://www.dermatology.labiomed.org/page2.php?mytext=users/drcraft.txt

Scientific Interest(s):

Dr. Noah Craft's laboratory is interested in live bacterial therapeutic vaccines for melanoma and glioblastoma. He is also interested in immunomodulating molecules such as Toll-like receptor agonists as cancer vaccine adjuvants. These two approaches are used together and in combination with dendritic cell vaccines in translational and clinical studies against melanoma and glioblastoma.

Selected Cancer-Related Publications:

Prins RM, Bruhn KW, Craft N, Lin JW, Kim CH, Odesa SK, Miller JF, Liau LM. Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden. Neurosurgery. 2006; 58(1): 169-78; discussion 169-78.

Prins RM, Craft N, Bruhn KW, Khan-Farooqi H, Koya RC, Stripecke R, Miller JF, Liau LM. The TLR-7 agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to central nervous system antitumor immunity. J Immunol. 2006; 176(1): 157-64.

Simzar S, Rotunda AM, Craft N. Scrotal ulceration as a consequence of all-trans-retinoic acid (ATRA) for the treatment of acute promyelocytic leukemia. J Drugs Dermatol. 2005; 4(2): 231-2.

Craft N, Bruhn KW, Nguyen BD, Prins R, Lin JW, Liau LM, Miller JF. The TLR7 agonist imiquimod enhances the anti-melanoma effects of a recombinant Listeria monocytogenes vaccine. J Immunol. 2005; 175(3): 1983-90.

Craft N, Bruhn KW, Nguyen BD, Prins R, Liau LM, Collisson EA, De A, Kolodney MS, Gambhir SS, Miller JF. Bioluminescent imaging of melanoma in live mice. J Invest Dermatol. 2005; 125(1): 159-65.