Scientific Interest(s):
Dr. Carolyn Crandall's research focuses on breast cancer risk (e.g., her mammographic density publications) and breast cancer survivorship issues, especially the intersection between breast cancer and menopause (e.g., her publications regarding hot flashes in breast cancer survivors and bone mineral density in breast cancer survivors).
She intends to continue two areas of investigation: first, the influence of breast cancer diagnosis and its therapy on menopause and osteoporosis in breast cancer survivors and secondly, strategies to target women at risk for breast cancer by continuing to study hormonal and genetic determinants of mammographic density. Her overall goals for these two lines of research are to enhance aspects of the quality of life of breast cancer survivors, and to help identify targets for intervention for high-risk women.
Selected Cancer-Related Publications:
Crandall C, Zheng Y, Karlamangla A, Sternfeld B, Habel L, Oestreicher N, Johnston J, Cauley J, Greendale G. The association between mammographic breast density and bone mineral density. Study of Women's Health Across the Nation. 2007; 17:575-83.
Crandall CJ, Karlamangla A, Huang MH, Ursin G, Guan M, Greendale GA. Association of new-onset breast discomfort with an increase in mammographic density during hormone therapy. Archives of Internal Medicine. 2006; 166:1578-1584.
Crandall C, Palla S, Reboussin BA, Ursin G, Greendale GA. Positive association between mammographic breast density and bone mineral density in the Postmenopausal Estrogen/Progestin Interventions Study. Breast Cancer Res. 2005; 7(6): R922-8.
Crandall C, Petersen L, Ganz PA, Greendale GA. Bone mineral density and adjuvant therapy in breast cancer survivors. Breast Cancer Res Treat. 2004; 88(3): 257-61.
Crandall C, Petersen L, Ganz PA, Greendale GA. Association of breast cancer and its therapy with menopause-related symptoms. Menopause. 2004; 11(5): 519-30.