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JCCC Member Directory

Helena Chang, M.D.
Helena Chang, M.D.

Specialty:

Cancer/Surgical Oncology
Surgery General

General Information:

Gender:
Female
Language(s):
Chinese, English

Affiliation(s):

Director, Revlon/UCLA Breast Center
Professor, Department of Surgery
Physician, Department of Surgery, Surgical Oncology
Member, JCCC Signal Transduction and Therapeutics Program Area

Hospital Affiliation(s):

Ronald Reagan UCLA Medical Center

Education:

Fellowship:
Surgery/Oncology, Memorial Sloan-Kettering Cancer Center, 1986 - 1988
Residency:
Surgery, Episcopal Hospital, 1981 - 1986
Medical Degree:
M.D., Temple University School of Medicine, 1981

Contact Information:

Surgery:
(310) 794-7788 Patient appointments
Surgical Oncology:
(310) 206-6909 Information and referral
(310) 206-6931 Follow-up appointments
(310) 825-2644 Referring physician
Revlon/UCLA Breast Center:
(310) 825-2144 Patient referral coordinator
Phone:
(310) 794-5624
Email:
hchang@mednet.ucla.edu

Practice Information:

Clinical Interest(s):
Breast

Scientific Interest(s):

Dr. Helena Chang's long-term research interest is in the development of immunotherapy in treating adult ductal epithelial cancer. Chang has developed several recombinant live vaccines that actively secrete a tumor antigen and human cytokines. The role of these vaccines in human cancer treatment and prevention is being investigated. The biological activity of the targeted tumor antigen (MUC-1 peptide) and its involvement in cancer invasion and metastases is being characterized by her research team. She is also working closely with clinician-scientists and basic researchers in studies that characterize breast cancer behavior and develop molecular classifications for locally advanced breast cancer.

Selected Cancer-Related Publications:

He J, Gornbein J, Shen D, Lu M, Rovai LE, Shau H, Katz J, Whitelegge JP, Faull KF, Chang HR. Detection of breast cancer biomarkers in nipple aspirate fluid by SELDI-TOF and their identification by combined liquid chromatography-tandem mass spectrometry. Int J Oncol. 2007; 30(1): 145-54.

Shen D, Nooraie F, Elshimali Y, Lonsberry V, He J, Bose S, Chia D, Seligson D, Chang HR, Goodglick L. Decreased expression of annexin A1 is correlated with breast cancer development and progression as determined by a tissue microarray analysis. Hum Pathol. 2006; 37(12): 1583-91.

Shen D, He J, Chang HR. In silico identification of breast cancer genes by combined multiple high throughput analyses. Int J Mol Med. 2005; 15(2): 205-12.

Tsai HC, Chang H, Barsky SH. Atypical ductal hyperplasia presenting as pseudomicrocalcifications. Breast J. 2003; 9(1): 39-40.

Zhang L, Shao ZM, Beatty P, Sartippour M, Wang HJ, Elashoff R, Chang H, Brooks MN. The use of oxytocin in nipple fluid aspiration. Breast J. 2003; 9(4): 266-8.

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