Scientific Interest(s):
Dr. Michael Phelps’ research focuses on the integration of the biology of disease, in vivo (PET imaging) and in vitro molecular diagnostics and molecular and cellular therapeutics in cancer, from pre-clinical to clinical and patient care.
Selected Cancer-Related Publications:
Laing RE, Walter MA, Campbell DO, Herschman HR, Satyamurthy N, Phelps ME, Czernin J, Witte ON, Radu CG. Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2847-52. Epub 2009 Feb 5.
Radu CG, Shu CJ, Nair-Gill E, Shelly SM, Barrio JR, Satyamurthy N, Phelps ME, Witte ON. Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2'-deoxycytidine analog. Nat Med. 2008 Jul;14(7):783-8. Epub 2008 Jun 8.
Gambhir SS, Bauer E, Black ME, Liang Q, Kokoris MS, Barrio JR, Iyer M, Namavari M, Phelps ME, Herschman HR. A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2785-90.
Phelps ME. Positron emission tomography provides molecular imaging of biological processes. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9226-33.
Guerrero TM, Hoffman EJ, Dahlbom M, Cutler PD, Hawkins RA, Phelps ME. Characterization of a whole body imaging technique for PET. IEEE 37:676-680, 1990.