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JCCC Member Directory

Tatiana Segura, Ph.D.
Tatiana Segura, Ph.D.

Affiliation(s):

Assistant Professor, Department of Chemical and Biomolecular Engineering
Member, JCCC Cancer Nanotechnology Program Area

Contact Information:

Phone:
(310) 206-3980
Email:

Scientific Interest(s):

Dr. Tatiana Segura's laboratory designs and synthesizes biomaterials that have a control ECM in order to study cancer cell biology. They seek to use these materials for novel delivery strategies for DNA therapeutics that target cancer cells.

Selected Cancer-Related Publications:

Anderson SM, Siegman SN, Segura T. The effect of vascular endothelial growth factor (VEGF) presentation within fibrin matrices on endothelial cell branching. Biomaterials. 2011 Oct;32(30):7432-43. Epub 2011 Jul 23

Gojgini S, Tokatlian T, Segura T. Utilizing cell-matrix interactions to modulate gene transfer to stem cells inside hyaluronic acid hydrogels. Mol Pharm. 2011 Oct 3;8(5):1582-91. Epub 2011 Aug 24

Lei Y, Gojgini S, Lam J, Segura T. The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels. Biomaterials. 2011 Jan;32(1):39-47. Epub 2010 Oct 12

Yan M, Du J, Gu Z, Liang M, Hu Y, Zhang W, Priceman S, Wu L, Zhou ZH, Liu Z, Segura T, Tang Y, Lu Y. A novel intracellular protein delivery platform based on single-protein nanocapsules. Nat Nanotechnol. 2010 Jan;5(1):48-53. Epub 2009 Nov 22

Anderson SM, Chen TT, Iruela-Arispe ML, Segura T. The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF. Biomaterials. 2009 Sep;30(27):4618-28. Epub 2009 Jun 21