UCLA's Jonsson Comprehensive Cancer Center : JCCC Member Directory

Jiaoti Huang, M.D., Ph.D.

Specialty:

Pathology

General Information:

Gender:	Male
Language(s):	English, Chinese

Affiliation(s):

Professor and Director of Urologic Pathology, Department of Pathology and Laboratory Medicine

Co-Director, Pathway Pathology Laboratory, Institute for Molecular Medicine

Member, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research

Member, JCCC Cancer and Stem Cell Biology Program Area

Hospital Affiliation(s):

Ronald Reagan UCLA Medical Center

Education:

Fellowship:	Anatomic and Clinical Pathology, Memorial Sloan-Kettering Cancer Center, 1999 - 2000
Residency:	Anatomic and Clinical Pathology, New York University School of Medicine, 1995 - 1999
Medical Degree:	M.D., Anhui Medical University, 1983
Degree:	Ph.D., New York University School of Medicine, 1991

Certification(s):

Medical Board Certification(s):	Anatomic Pathology and Clinical Pathology, American Board of Pathology, 2000

Contact Information:

Phone:	(310) 267-2264
Email:	JiaotiHuang@mednet.ucla.edu
Website:	http://faculty.pathology.ucla.edu/institution/personnel?personnel%5fid=622586

Practice Information:

Clinical Interest(s):	Tumors of prostate, bladder, kidney and testis

Scientific Interest(s):

Dr. Jiaoti Huang’s laboratory has been studying the molecular mechanisms by which prostate cancer becomes insensitive to hormonal therapy and progresses to castration resistant tumors. His lab is actively engaged in drug discovery and in developing tumor models that can be used for the development of tools used in diagnosis, imaging, prevention and therapy of prostate cancer.

Selected Cancer-Related Publications:

Huang J, Witte ON. A seminal finding for prostate cancer? N Engl J Med. 2010 Jan 14;362(2):175-6.

Lawson DA, Zong Y, Memarzadeh S, Xin L, Huang J, Witte ON. Basal epithelial stem cells are efficient targets for prostate cancer initiation. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2610-5. Epub 2010 Jan 25.

Palapattu GS, Wu C, Silvers CR, Martin HB, Williams K, Salamone L, Bushnell T, Huang LS, Yang Q, Huang J. Selective expression of CD44, a putative prostate cancer stem cell marker, in neuroendocrine tumor cells of human prostate cancer. Prostate. 2009 May 15;69(7):787-98.

Simon RA, di Sant'Agnese PA, Huang LS, Xu H, Yao JL, Yang Q, Liang S, Liu J, Yu R, Cheng L, Oh WK, Palapattu GS, Wei J, Huang J. CD44 expression is a feature of prostatic small cell carcinoma and distinguishes it from its mimickers. Hum Pathol. 2009 Feb;40(2):252-8. Epub 2008 Oct 5.

Wu C, Huang J. Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway is essential for neuroendocrine differentiation of prostate cancer. J Biol Chem. 2007 Feb 9;282(6):3571-83. Epub 2006 Dec 4.