JCCC and Broad Stem Cell Research Center Seminar Featuring Dr. Emmanuelle Passegue
The Many Faces of Hematopoietic Stem Cells
12:00 PM - 1:00 PM
10833 Le Conte Ave.
Los Angeles, California 90095
Emmanuelle Passegue, Ph.D.
Associate Professor, Department of Medicine, Hematology-Oncology
Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
University of California at San Francisco
Dr. Passegue's research focuses on deciphering the cellular and molecular mechanisms governing normal blood function and to unravel how they become deregulated in myeloid malignancies using the mouse as a model system. We are particularly interested in understanding how normal hematopoietic stem cells (HSCs) can become leukemia-initiating stem cells (LCSs), which promote tumor growth and disease recurrence, and to search for ways to prevent their transformation. Current projects in the laboratory study the implication of apoptosis, autophagy, immune regulation, DNA repair mechanisms and differentiation pathways in the maintenance and regulation of normal HSCs and tranformed LSCs.
Light lunch served
Co-sponsored by the JCCC & the Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research