UCLA's Jonsson Comprehensive Cancer Center : JCCC Member Directory

Noriyuki Kasahara, M.D., Ph.D.

Affiliation(s):

Professor, Department of Medicine, Department of Molecular and Medical Pharmacology

Director, CURE Vector Core and JCCC Vector Core Shared Resource

Member, JCCC Tumor Immunology Program Area

Contact Information:

Phone:	(310) 825-7112
Email:	nkasahara@mednet.ucla.edu

Scientific Interest(s):

Dr. Noriyuki Kasahara's research is focused on molecular therapeutics and gene transfer vector development.

Selected Cancer-Related Publications:

Hiraoka K, Kimura T, Logg CR, Tai CK, Haga K, Lawson GW, Kasahara N. Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model. Cancer Res. 2007; 67(11): 5345-53.

Tai CK, Wang WJ, Chen TC, Kasahara N. Single-shot, multicycle suicide gene therapy by replication-competent retrovirus vectors achieves long-term survival benefit in experimental glioma. Mol Ther. 2005; 12(5): 842-51.

Logg CR, Tai CK, Logg A, Anderson WF, Kasahara N. A uniquely stable replication-competent retrovirus vector achieves efficient gene delivery in vitro and in solid tumors in vivo. Human Gene Therapy. 2002; 12:921-932.

ShichinoheT, Bochner BH, Mizutani K, Nishida M, Hegerich-Gilliam S, Naldini L, Kasahara N. Development of lentivirus vectors for anti-angiogenic gene therapy. Cancer Gene Therapy. 2002; 8:879-889.

Kasahara N, Dozy A, Kan YW. Tissue-specific targeting of retroviral vectors via ligand-receptor interaction. Science. 1994; 266:1373-1376.