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Matthew B. Rettig, M.D.
Matthew B. Rettig, M.D.


Internal Medicine
Medical Oncology

General Information:



Associate Professor in Residence, Department of Medicine, Hematology/Oncology
Member, JCCC Cancer and Stem Cell Biology Program Area

Hospital Affiliation(s):

Ronald Reagan UCLA Medical Center


Internal Medicine, UCLA School of Medicine, 1993 - 1996
Internal Medicine, University of Washington School of Medicine, 1991 - 1993
Internal Medicine, LAC+USC Medical Center, 1990 - 1991
Medical Degree:
M.D., Duke University School of Medicine, 1990


Board Certification(s):
Medical Oncology, American Board of Internal Medicine, 1998
Internal Medicine, American Board of Internal Medicine, 1996

Contact Information:

(310) 206-2436

Scientific Interest(s):

Dr. Matthew Rettig's research focuses on the molecular and cellular biology of multiple myeloma, the role of human herpesvirus-8 in pathogenesis of myeloma and latent human herpesvirus-8 proteins that upregulate the transcription of cellular interleukin-6.

Selected Cancer-Related Publications:

An J, Rettig MB. Epidermal growth factor receptor inhibition sensitizes renal cell carcinoma cells to the cytotoxic effects of bortezomib. Mol Cancer Ther. 2007; 6(1): 61-9.

An J, Rettig MB. Mechanism of von Hippel-Lindau protein-mediated suppression of nuclear factor kappa B activity. Mol Cell Biol. 2005; 25(17): 7546-56.

Conde FA, Sarna L, Oka RK, Vredevoe DL, Rettig MB, Aronson WJ. Age, body mass index, and serum prostate-specific antigen correlate with bone loss in men with prostate cancer not receiving androgen deprivation therapy. Urology. 2004; 64(2): 335-40.

An J, Sun YP, Adams J, Fisher M, Belldegrun A, Rettig MB. Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) alpha, and TNF-related apoptosis-inducing ligand in prostate cancer. Clin Cancer Res. 2003; 9(12): 4537-45.

An J, Sun Y, Sun R, Rettig MB. Kaposi's sarcoma-associated herpesvirus encoded vFLIP induces cellular IL-6 expression: the role of the NF-kappaB and JNK/AP1 pathways. Oncogene. 2003; 22(22): 3371-85.