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Noah Craft, M.D., Ph.D.
Noah Craft, M.D., Ph.D.

General Information:

Gender:
Male
Language(s):
English

Affiliation(s):

Assistant Professor, Harbor-UCLA Department of Medicine, Division of Dermatology
Associate Program Director, Dermatology
Director, Guenther Center for Immunotherapeutics Research
Member, Los Angeles Biomedical Research Institute
Member, JCCC Tumor Immunology Program Area

Education:

Fellowship:
Dermatology and Microbiology, Immunology, and Molecular Genetics, UCLA, 2001 - 2005
Residency:
Dermatology, UCLA/West Los Angeles Veterans Affairs Medical Center, 2001 - 2005
Internship:
Internal Medicine, UCLA/Olive View County Hospital, 2000 - 2001
Medical Degree:
M.D., UCLA School of Medicine, 2000
Degree:
Ph.D., UCLA Molecular Biology Institute, 2000

Contact Information:

Phone:
(310) 781-1447
Email:
Website:

Scientific Interest(s):

Dr. Noah Craft's laboratory is interested in live bacterial therapeutic vaccines for melanoma and glioblastoma. He is also interested in immunomodulating molecules such as Toll-like receptor agonists as cancer vaccine adjuvants. These two approaches are used together and in combination with dendritic cell vaccines in translational and clinical studies against melanoma and glioblastoma.

Selected Cancer-Related Publications:

Tietze JK, Wilkins DE, Sckisel GD, Bouchlaka MN, Alderson KL, Weiss JM, Ames E, Bruhn KW, Craft N, Wiltrout RH, Longo DL, Lanier LL, Blazar BR, Redelman D, Murphy WJ. Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy. Blood. 2012 Mar 29;119(13):3073-83. Epub 2012 Jan 17

Narayan R, Nguyen H, Bentow JJ, Moy L, Lee DK, Greger S, Haskell J, Vanchinathan V, Chang PL, Tsui S, Konishi T, Comin-Anduix B, Dauphine C, Vargas HI, Economou JS, Ribas A, Bruhn KW, Craft N. Immunomodulation by imiquimod in patients with high-risk primary melanoma. J Invest Dermatol. 2012 Jan;132(1):163-9. Epub 2011 Aug 18

Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, Jhaveri N, Zhu G, Ye R, Liu Z, Bruhn KW, Craft N, Groshen S, Hofman FM, Lee AS. A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis. Cancer Res. 2011 Apr 15;71(8):2848-57. Epub 2011 Apr 5

Vo DD, Prins RM, Begley JL, Donahue TR, Morris LF, Bruhn KW, de la Rocha P, Yang MY, Mok S, Garban HJ, Craft N, Economou JS, Marincola FM, Wang E, Ribas A. Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824. Cancer Res. 2009 Nov 15;69(22):8693-9. Epub 2009 Oct 27

Bruhn KW, Craft N, Miller JF. Listeria as a vaccine vector. Microbes Infect. 2007 Aug;9(10):1226-35. Epub 2007 May 7