Skip to page body Patient Care Survivorship Research Cancer Types News Giving Community Partners Clinical Trials
UCLA's Jonsson Comprehensive Cancer Center
Take the Jonsson Cancer Center Site Survey

JCCC Member Directory

Gustavo A. Miranda-Carboni, Ph.D.
Gustavo A. Miranda-Carboni, Ph.D.

Affiliation(s):

Assistant Professor, Department of Obstetrics and Gynecology
Member, JCCC Signal Transduction and Therapeutics Program Area

Contact Information:

Phone:
(310) 794-1216
Email:

Scientific Interest(s):

Dr. Gustavo Miranda-Carboni's reasearch interests are on modeling human breast cancer using mouse models of the Wnt/beta-catenin signaling pathway. His translation model is for a subset of human breast cancers known as Triple-Negative which afflicts African-American women three times higher than other ethnic groups. This type of breast cancer is highly aggressive, lacks any known therapeutics and afflicts pre-menopausal women at ~33 percent of the time upon diagnosis.

Selected Cancer-Related Publications:

Wend P, Wend K, Krum SA, Miranda-Carboni GA. The role of WNT10B in physiology and disease. Acta Physiol (Oxf). 2012 Jan;204(1):34-51. Epub 2011 May 7

Miranda-Carboni GA, Guemes M, Bailey S, Anaya E, Corselli M, Peault B, Krum SA. GATA4 regulates estrogen receptor-alpha-mediated osteoblast transcription. Mol Endocrinol. 2011 Jul;25(7):1126-36. Epub 2011 May 12

Krum SA, la Rosa Dalugdugan E, Miranda-Carboni GA, Lane TF. BRCA1 Forms a Functional Complex with ?-H2AX as a Late Response to Genotoxic Stress. J Nucleic Acids. 2010 Sep 27;2010.

Stevens JR, Miranda-Carboni GA, Singer MA, Brugger SM, Lyons KM, Lane TF. Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells. J Bone Miner Res. 2010 Oct;25(10):2138-47.

Miranda-Carboni GA, Krum SA, Yee K, Nava M, Deng QE, Pervin S, Collado-Hidalgo A, Galic Z, Zack JA, Nakayama K, Nakayama KI, Lane TF. A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes Dev. 2008 Nov 15;22(22):3121-34.