Skip to page body Patient Care Survivorship Research Cancer Types News Giving Community Partners Clinical Trials
UCLA's Jonsson Comprehensive Cancer Center
Take the Jonsson Cancer Center Site Survey

JCCC Member Directory

Yvonne Y. Chen, Ph.D.
Yvonne Y. Chen, Ph.D.


Assistant Professor, Department of Chemical and Biomolecular Engineering
Member, JCCC Tumor Immunology Program Area

Contact Information:

(310) 825-2816

Scientific Interest(s):

Dr. Yvonne Chen's research focuses on applying molecular and synthetic biology techniques to rewire and construct novel biological circuits for applications in health and medicine, particularly in cell-based immunotherapy. Current projects include the engineering of next-generation chimeric antigen receptors and rewiring cytokine signaling pathways for adoptive T-cell therapy against cancer.

Selected Cancer-Related Publications:

Chen YY, Galloway KE, Smolke CD. Synthetic biology: advancing biological frontiers by building synthetic systems. Genome Biol. 2012 Feb 20;13(2):240. doi: 10.1186/gb-2012-13-2-240.

Chen YY, Smolke CD. From DNA to targeted therapeutics: bringing synthetic biology to the clinic. Sci Transl Med. 2011 Oct 26;3(106):106ps42. doi: 10.1126/scitranslmed.3002944.

Chen YY, Jensen MC, Smolke CD. Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8531-6. doi: 10.1073/pnas.1001721107. Epub 2010 Apr 26.