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JCCC Member Directory

Alison R. Frand, Ph.D.
Alison R. Frand, Ph.D.

Affiliation(s):

Assistant Professor, Department of Biological Chemistry
Member, JCCC Cancer and Stem Cell Biology Program Area

Contact Information:

Phone:
(310) 206-0662
Email:
Website:

Scientific Interest(s):

Dr. Alison Frand’s lab studies molecules and pathways that regulate epidermal stem cell and extracellular matrix dynamics in the physiologic context of the molting cycle of the model nematode C. elegans.

Selected Cancer-Related Publications:

Monsalve GC, Frand AR. Toward a unified model of developmental timing: A "molting" approach. Worm. 2012 Oct 1;1(4):221-30. doi: 10.4161/worm.20874.

Gomez F, Monsalve GC, Tse V, Saiki R, Weng E, Lee L, Srinivasan C, Frand AR, Clarke CF. Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli. BMC Microbiol. 2012 Dec 20;12:300. doi: 10.1186/1471-2180-12-300.

Moissiard G, Cokus SJ, Cary J, Feng S, Billi AC, Stroud H, Husmann D, Zhan Y, Lajoie BR, McCord RP, Hale CJ, Feng W, Michaels SD, Frand AR, Pellegrini M, Dekker J, Kim JK, Jacobsen SE. MORC family ATPases required for heterochromatin condensation and gene silencing. Science. 2012 Jun 15;336(6087):1448-51. doi: 10.1126/science.1221472. Epub 2012 May 3.

Monsalve GC, Van Buskirk C, Frand AR.LIN-42/PERIOD controls cyclical and developmental progression of C. elegans molts. Curr Biol. 2011 Dec 20;21(24):2033-45. doi: 10.1016/j.cub.2011.10.054. Epub 2011 Dec 1.

Russel S, Frand AR, Ruvkun G. Regulation of the C. elegans molt by pqn-47. Dev Biol. 2011 Dec 15;360(2):297-309. doi: 10.1016/j.ydbio.2011.09.025. Epub 2011 Oct 1.