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JCCC Member Directory

James Economou, M.D., Ph.D.
James Economou, M.D., Ph.D.

Specialty:

Cancer/Surgical Oncology
Surgery General

General Information:

Gender:
Male
Language(s):
English

Affiliation(s):

Chief, Surgical Oncology
Professor, Surgery
Professor, Microbiology, Immunology and Molecular Genetics
Professor, Molecular and Medical Pharmacology
Member, JCCC Tumor Immunology Program Area

Education:

Residency:
Surgery, UCSF School of Medicine, 1983-1986
Internship:
Surgery, David Geffen School of Medicine at UCLA, 1980-1983
Medical Degree:
M.D., Johns Hopkins University, 1980
Degree:
Ph.D., Johns Hopkins University, 1980

Certification(s):

Medical Board Certification(s):
Surgery, American Board of Surgery, 1987

Contact Information:

Phone:
(310) 825-2644
Email:
jeconomou@mednet.ucla.edu

Scientific Interest(s):

Dr. James Economou coordinates the Human Gene Therapy Program with Dr. William McBride. His research interests include melanoma and hepatoma clinical trials, vector design, in vivo gene transfer and cytokine biology.

Selected Cancer-Related Publications:

Butterfield LH, Comin-Anduix B, Vujanovic L, Lee Y, Dissette VB, Yang JQ, Vu HT, Seja E, Oseguera DK, Potter DM, Glaspy JA, Economou JS, Ribas A. Adenovirus MART-1-engineered autologous dendritic cell vaccine for metastatic melanoma. J Immunother. 2008 Apr;31(3):294-309.

Comin-Anduix B, Lee Y, Jalil J, Algazi A, de la Rocha P, Camacho LH, Bozon VA, Bulanhagui CA, Seja E, Villanueva A, Straatsma BR, Gualberto A, Economou JS, Glaspy JA, Gomez-Navarro J, Ribas A. Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma. J Transl Med. 2008 May 1;6:22.

Chhabra A, Yang L, Wang P, Comin-Anduix B, Das R, Chakraborty NG, Ray S, Mehrotra S, Yang H, Hardee CL, Hollis R, Dorsky DI, Koya R, Kohn DB, Ribas A, Economou JS, Baltimore D, Mukherji B. CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model. J Immunol. 2008 Jul 15;181(2):1063-70.

Butterfield LH, Ribas A, Potter DM, Economou JS. Spontaneous and vaccine induced AFP-specific T cell phenotypes in subjects with AFP-positive hepatocellular cancer. Cancer Immunol Immunother. 2007 Dec;56(12):1931-43. Epub 2007 May 24.

Straatsma BR, Nusinowitz S, Young TA, Gordon LK, Chun MW, Rosen C, Seja E, Economou JS, Glaspy JA, Bozon V, Gomez-Navarro J, Ribas A. Surveillance of the eye and vision in clinical trials of CP-675,206 for metastatic melanoma. Am J Ophthalmol. 2007; 143(6): 958-969.

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