Skip to page body Patient Care Survivorship Research Cancer Types News Giving Community Partners Clinical Trials
UCLA's Jonsson Comprehensive Cancer Center
Take the Jonsson Cancer Center Site Survey

JCCC Member Directory

John H. Fessler, Ph.D.
John H. Fessler, Ph.D.

Affiliation(s):

Professor Emeritus, Department of Molecular, Cell, and Developmental Biology
Member, JCCC Cancer and Stem Cell Biology Program Area

Contact Information:

Phone:
(310) 825-4267
Email:

Scientific Interest(s):

Dr. John Fessler's research seeks to understand the molecular biology of how drosophila embryo cells collaborate to form a tissue. Basement membranes are fundamental to tissue construction. These thin nets of specialized, conserved extracellular proteins underlie epithelial cells and surround muscles and nerves. Fessler's lab has isolated, cloned and sequenced several of the component proteins, such as laminin and collagen, and is now studying mutant forms, the control of production and interactions during development. Three new proteins are of special interest: peroxidasin, papilin and a drosophila ADAMTS protease.