Dr. Margaret Stuber studies the emotional responses of children and their families to life-threatening illness. These include symptoms of post-traumatic stress disorder, as well as the ability to find meaning in adversity. As part of the National Child Traumatic Stress Network, Stuber helps hospitals learn how to help children and families deal with cancer diagnosis and treatment. Through her roles in medical student education and grants from the National Cancer Institute and Centers for Disease Control and Prevention, Stuber also helps develop curriculum to teach future doctors how to better understand people dealing with cancer and other life-threatening illnesses.

Stuber is one of the pioneers in the understanding of post-traumatic stress response to life-threatening pediatric illnesses in children and their parents. She has studied the prevalence, correlations and prevention of these symptoms in survivors of childhood cancer and their parents, and well as in pediatric solid organ transplants.

Stuber is currently focused on curricular development for medical students. She is actively engaged in development of curricular elements addressing cancer survivors, and has recently moved into curricular development in spirituality and complementary and alternative medicine.