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Chih-Ming Ho, Ph.D.
Chih-Ming Ho, Ph.D.


Professor, Department of Mechanical and Aerospace Engineering
Ben Rich-Lockheed Martin Chair Professor, School of Engineering
UCLA Distinguished Professor
Director, Center for Cell Control (CCC), NIH Nanomedicine Center
Member, JCCC Cancer Nanotechnology Program Area

Contact Information:

(310) 825-9993

Scientific Interest(s):

Dr. Chih-Ming Ho's research focuses on controlling the position of macromolecules, DNA/RNA, proteins and supermolecules for facilitating function processes such as molecular recognition, biochemical reactions and self assembly. As these processes always take place in fluid flows, a key goal is the creation of nano-fluidic technologies to handle nanoscale molecules in microscale reactors. He seeks to understand the interactions between intermolecular force fields and global forces to provide the path for developing efficient nano-fluidic technologies. Ultimately, nano-fluidics form the backbone for a wide spectrum of bio-nano application such as genosensing, drug discovery and health maintenance.

Selected Cancer-Related Publications:

Yu F, Al-Shyoukh I, Feng J, Li X, Liao CW, Ho CM, Shamma JS, Sun R. Control of Kaposi's sarcoma-associated herpesvirus reactivation induced by multiple signals. PLoS One. 2011 Jun 28;6(6):e20998.

Wei F, Liao W, Xu Z, Yang Y, Wong DT, Ho CM. Bio/abiotic interface constructed from nanoscale DNA dendrimer and conducting polymer for ultrasensitive biomolecular diagnosis. Small. 2009 Aug 3;5(15):1784-90.

Sun CP, Usui T, Yu F, Al-Shyoukh I, Shamma J, Sun R, Ho CM. Integrative systems control approach for reactivating Kaposi's sarcoma-associated herpesvirus (KSHV) with combinatory drugs. Integr Biol (Camb). 2009 Jan;1(1):123-30.

Wong PK, Yu F, Shahangian A, Cheng G, Sun R, Ho CM. Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm. Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5105-10. Epub 2008 Mar 20.

Li N, Ho CM. Aptamer-based optical probes with separated molecular recognition and signal transduction modules. J Am Chem Soc. 2008 Feb 27;130(8):2380-1. Epub 2008 Feb 5