UCLA's Jonsson Comprehensive Cancer Center : JCCC Member Directory

Phioanh (Leia) Nghiemphu, M.D.

Specialty:

Neuro-Oncology

General Information:

Gender:	Female
Language(s):	English, Vietnamese

Affiliation(s):

Assistant Clinical Professor, Department of Neurology, Neurological Services, Neuro-Oncology Program, Brain Tumor Program

Member, JCCC Signal Transduction and Therapeutics Program Area

Hospital Affiliation(s):

Ronald Reagan UCLA Medical Center

Education:

Fellowship:	Neuro-Oncology, UCLA Neuro-Oncology Program, 2003-2006
Residency:	Neurology, Stanford Medical Center, 2000-2003
Internship:	Medicine, Beth Israel Medical Center, New York, NY 1999-2000
Medical Degree:	M.D., Albert Einstein College of Medicine, 1999

Certification(s):

Medical Board Certification(s):	Neurology, Neuro-Oncology, American Board of Psychiatry and Neurology, 2004

Contact Information:

Phone:	(310) 825-5321 (information) (310) 206-6909 (new patient)
Email:	leian@ucla.edu
Website:	http://www.neurooncology.ucla.edu/

Practice Information:

Clinical Interest(s):	Brain Tumors Neuro-Oncology

Scientific Interest(s):

Dr. Phioanh Nghiemphu’s research interest focuses on finding individualized molecular therapy for patients with malignant brain cancer. Her main goal lies in designing molecularly driven clinical trials that can provide tissues to understand mechanisms of response and resistance to molecular therapies for brain cancer. Her works to date mainly concentrate on aberrant pathways in glioblastoma and anti-angiogenic treatments.

Selected Cancer-Related Publications:

Nghiemphu PL, Liu W, Lee Y, Than T, Graham C, Lai A, Green RM, Pope WB, Liau LM, Mischel PS, Nelson SF, Elashoff R, Cloughesy TF. Bevacizumab and chemotherapy for recurrent glioblastoma: a single-institution experience. Neurology. 2009 Apr 7;72(14):1217-22.

Pope WB, Chen JH, Dong J, Carlson MR, Perlina A, Cloughesy TF, Liau LM, Mischel PS, Nghiemphu P, Lai A, Nelson SF. Relationship between gene expression and enhancement in glioblastoma multiforme: exploratory DNA microarray analysis. Radiology. 2008 Oct;249(1):268-77.

Nghiemphu PL, Green RM, Pope WB, Lai A, Cloughesy TF. Safety of anticoagulation use and bevacizumab in patients with glioma. Neuro Oncol. 2008 Jun;10(3):355-60. Epub 2008 Apr 24.

Cloughesy TF, Yoshimoto K, Nghiemphu P, Brown K, Dang J, Zhu S, Hsueh T, Chen Y, Wang W, Youngkin D, Liau L, Martin N, Becker D, Bergsneider M, Lai A, Green R, Oglesby T, Koleto M, Trent J, Horvath S, Mischel PS, Mellinghoff IK, Sawyers CL. Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS Med. 2008 Jan 22;5(1):e8.

Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, Du J, Kau T, Thomas RK, Shah K, Soto H, Perner S, Prensner J, Debiasi RM, Demichelis F, Hatton C, Rubin MA, Garraway LA, Nelson SF, Liau L, Mischel PS, Cloughesy TF, Meyerson M, Golub TA, Lander ES, Mellinghoff IK, Sellers WR. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20007-12. Epub 2007 Dec 6.