Calendar Review
JCCC “Leaders in the Field” Seminar Series Featuring Dr. Joseph Costello
The Evolving Genomic Landscape of IDH1 Mutant Tumors
3/26/2013
12:00 PM - 1:00 PM
Free
73-105 CHS
10833 Le Conte Ave.
Los Angeles, California 90095

Presented by:
Joseph Costello, Ph.D.
Director, Epigenetics Division, Cell Cycling and Signaling Program
Karen Osney Brownstein Endowed Chair in Molecular Neuro-Oncology
University of California, San Francisco
Dr. Costello's laboratory investigates the role of genetic and epigenetic alterations in the development of sporadic cancers, with a focus on brain tumors. Most sporadic cancers have been described by molecular pathways involving gain and loss of chromosomal regions corresponding to oncogene activation and tumor suppressor gene inactivation, respectively. Such genetic characterizations of sporadic tumors do not take into account epigenetic alterations that may similarly result in abnormal loss or gain of gene activity.
Light lunch served
Sponsored by the JCCC